04 Biomedical, Skin & Dental Technologies
The Global Reach | Patent Citation Archive
The original IMX technologies also appear in subsequent patent literature addressing biofabrication, biomedical delivery, skin-treatment systems, customized dental materials, and hydrogel dispensing.
These records document technical references to earlier inventions involving computerized formulation, precision dispensing, robotic positioning, and material handling.
The citations establish connections within the patent literature without independently demonstrating technology adoption, licensing, or commercial collaboration.
Biofabrication
& Three-Dimensional Biomaterial Technologies
Advanced Solutions
Life Sciences
Advanced Solutions Life Sciences' US 11,768,481 B2 — System and Workstation for the Design, Fabrication and Assembly of Bio-Material Constructs was granted in September 2023.
The invention describes a computer-assisted bioassembly system integrating tissue-design software with a robotic fabrication workstation.
Its technology includes multi-axis robotic positioning and controlled deposition of materials to fabricate three-dimensional biological and non-biological constructs.
The patent directly cites US 2006/0124196 A1 — Automated Customized Cosmetic Dispenser, an earlier IMX invention naming Julie Bartholomew as an inventor.
A related patent in the same family, US 11,112,769 B2, was granted in September 2021.
These records document the appearance of the original IMX automated-dispensing technology in subsequent patent literature concerning robotic biofabrication, material deposition, and three-dimensional biomaterial construction.
Biomedical
Delivery & Intradermal Technologies
Aquavit Pharmaceuticals
Aquavit Pharmaceuticals' US 11,202,753 B1 — Systems and Methods for Generating Immune Responses in Subjects Using Microchannel Delivery Devices was granted in December 2021.
The invention describes systems for delivering immunizing compositions through microchannel-based devices, including microneedle arrangements designed for controlled administration into the skin.
Its cited references include US 2006/0124196 A1 — Automated Customized Cosmetic Dispenser, an earlier IMX publication.
A separate Aquavit international publication, WO 2021/016400 A1 — System and Method for Dual-Function Syringe Design Compounding Device for Personalized Treatments, describes systems for preparing individualized treatment formulations using syringe-based compounding mechanisms.
That publication also cites US 2006/0124196 A1, along with US 8,573,263 B2 — Apparatus and Method for Custom Cosmetic Dispensing.
Together, these records establish direct references to the earlier IMX dispensing technologies in later patent literature involving intradermal delivery, biomedical preparation, and personalized pharmaceutical compounding.
Skin Treatment, Photopatterning & Hydrogel Technologies
LG Electronics —
Hydrogel Dispensing
LG Electronics' US 11,172,750 B2 — Hydrogel Discharge Device was granted in November 2021.
A related Korean patent, KR 10-2478282 B1 — Hydrogel Discharge Apparatus and Method for the Same, was granted in December 2022.
The inventions describe systems for controlling the movement and dispensing of hydrogel formulations using electronic processing, material-delivery mechanisms, sensors, and regulated dispensing operations.
Both patent records cite US 2001/0047309 A1 — Nail Polish Color Selection System and Method, an earlier IMX publication naming Julie Bartholomew as a co-inventor.
These references document the appearance of original computerized cosmetic-selection technology in subsequent patent literature concerning hydrogel dispensing and customized skincare systems.
The U.S. and Korean patents are related members of the same international invention family.
Searete LLC —
Skin Treatment Including Patterned Light
US 8,157,807 B2 — Skin Treatment Including Patterned Light, granted in April 2012, originated from the earlier publication US 2006/0276860 A1.
The invention concerns applying controlled patterns of light to skin and using photoresponsive materials to produce localized effects.
Its specification discusses potential cosmetic and dermatologic applications, including skin markings and other specialized skin treatments.
The patent's cited references include US 6,672,341 B2 — Apparatus and Method for Custom Cosmetic Dispensing, an original IMX invention.
This establishes a direct patent-literature reference between earlier cosmetic-dispensing technology and subsequent research concerning photopatterning and localized skin treatment.
Searete LLC —
Holographic Tattoo
A separate Searete publication, US 2007/0032846 A1 — Holographic Tattoo, was published in February 2007.
The invention describes techniques for creating specialized optical effects in skin markings, including controlled placement of light-modulating materials to produce holographic visual effects.
Its cited references directly include US 6,672,341 B2 — Apparatus and Method for Custom Cosmetic Dispensing.
The application was subsequently abandoned, although its publication and citation record remain publicly accessible.
Together, these Searete records document references to original IMX technology in later patent literature addressing skin photopatterning, optical effects, and tattoo-related applications.
Dental Materials & Customized Dental Formulations
Stacey Ehlers —
Customized
Dental Fluoride Dispensing
Stacey Ehlers' US 7,648,050 B1 — Fluoride Dispenser was granted in January 2010.
The invention describes a dispensing apparatus that allows individually selected flavors or combinations of flavored fluoride compositions to be prepared for dental treatments.
Its patent references include two earlier IMX inventions:
-
US 2002/0179639 A1 — Point-of-Sale Body Powder Dispensing System
-
US 7,082,970 B2 — Apparatus and Method for Custom Cosmetic Dispensing
Both original patent publications identify Julie Bartholomew among their inventors.
These citations document the appearance of personalized cosmetic-dispensing inventions in subsequent patent literature concerning individualized dental-care formulations.
UV Polimer —
Dental Resin
Color Customization
UV Polimer's EP 4,563,221 A1 — Mixing and Coloring Device for Dental Resins was published on June 4, 2025.
The invention describes equipment for preparing dental resin materials through controlled pigment selection, mixing, and dispensing.
Its patent references include WO 2001/075586 A1 — Nail Polish Color Selection System and Method, an original IMX invention naming Julie Bartholomew as a co-inventor.
The European publication identifies the earlier IMX technology among its cited references.
This establishes a direct patent-literature connection between computerized cosmetic-color selection and subsequent technologies for preparing customized dental restorative materials.
The European application remains identified as pending in the patent record.
About These
Patent References
These records document references to original inventions associated with Julie R. Bartholomew, MD and historical IMX technologies.
References may appear in granted patents, published applications, patent citation lists, technical specifications, or related international patent-family records.
Multiple publications belonging to the same invention family are identified together where appropriate. Direct citations and family-level references are distinguished when relevant.
Patent citations establish documentary connections within the technical literature. They do not independently demonstrate commercial adoption, implementation, licensing, endorsement, or business relationships.
Company names and trademarks remain the property of their respective owners.